DRUG ACKNOWLEDGEMENT OF GENUVER™
Issued for Doctor’s convenience
To be used by Hospital, Laboratory & Registered Medical Practitioner
Each 5ml contains :-
PHARMACOKINETICS FACTS & ETHICS >>>
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.
Ofloxacin is approved for the treatment of bacterial infections such as:
- Acute bacterial exacerbations of chronic bronchitis
- Community-acquired pneumonia
- Uncomplicated skin and skin structure infections
- Nongonococcal urethritis and cervicitis
- Mixed Infections of the urethra and cervix
- Acute pelvic inflammatory disease
- Uncomplicated cystitis
- Complicated urinary tract infections
- Acute, uncomplicated urethral and cervical gonorrhea.
Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate (mostly in prokaryotes, in bacteria in particular) replicated DNA, thereby inhibiting bacterial cell division.
According to the product packing insert, ofloxacin is effective against the following microorganisms.
Aerobic Gram-positive microorganisms:
- Staphylococcus aureus (methicillin-susceptible strains)
- Streptococcus pneumoniae (penicillin-susceptible strains)
- Streptococcus pyogenes
Aerobic Gram-negative microorganisms
- Citrobacter koseri (Citrobacter diversus)
- Enterobacter aerogenes
- Escherichia coli
- Haemophilus influenzae
- Klebsiella pneumoniae
- Neisseria gonorrhoeae
- Proteus mirabilis
- Pseudomonas aeruginosa”
- Chlamydia trachomatis
Ornidazole is a drug that cures some protozoan infections. It is used by the poultry industry.
It has been investigated for use in Crohn’s disease after bowel resection.
Somnolence, headache, nausea, vomiting, dizziness, tremor, rigidity, poor coordination, seizures, tiredness, vertigo, temporary loss of consciousness & signs of sensory and mixed peripheral neuropathy, taste disturbances, abnormal LFTs, skin reactions.
Renal & hepatic impairment. CNS diseases e.g epilepsyor multiple sclerosis. May impair ability to drive or operate machinery. Pregnancy & lactation.
Potentiates effect of couramin- type oral anticoagulants. Prolonges the muscle- relaxants effecr of vecuronium bromide.
List of Contraindications
Caution when used during pregnancy
Caution when uswed during lactation
Information Not Available
Hypersensitivity to ornidazole or to other nitroimidazole derivatives.
DOSAGE >>> As directed by Physician
WARNING >>> FOR PAEDRITIC USE ONLY
Source : Wikipedia (Ofloxacin)
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